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Titlebook: Klinefelter’s Syndrome; Hans-Jürgen Bandmann,Reinhardt Breit,Elmar Perwein Conference proceedings 1984 Springer-Verlag Berlin Heidelberg 1

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,Immune Competence in Patients with Klinefelter’s Syndrome,rted to be associated with this syndrome. It appears that there is a frequent association of Klinefelter’s syndrome with autoimmune diseases and malignant neoplasms. Table 1 shows the cases reported in the literature. It is interesting to speculate as to the mechanisms responsible for this close ass
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,Klinefelter’s Syndrome and Testicular Tumors,sung and Heckman 1974). Thus the impression is given that combination of KS with tumors is common. In general, two factors are assumed to be responsible for this association: (a) chromosomal/genetic, and (b) hormonal/endocrine. Interactions and combinations of these two types of cause may frequently
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,Breast Carcinoma in Association with the Klinefelter’s Syndrome,ed an unusually high incidence of Klinefelter’s syndrome in men with breast carcinoma. Among 21 male patients with breast carcinoma, three were chromatin positive and had an abnormal sex chromosome complement. The incidence of breast carcinoma in males with Klinefelter’s syndrome was calculated to b
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,Taurodontism in Klinefelter’s Syndrome, (Witkop 1976). The fact that in several patients X chromosomal aneuploidy was initially suspected owing to the presence of taurodont molars (Feichtinger and Rossiwall 1977; Jaspers and Witkop 1980) between the ages of 7 and 12 years (e.g. patient in Fig. 2) raised hopes that routine panoramic X-ray
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,Breast Carcinoma in Association with the Klinefelter’s Syndrome,l. 1982; Robson et al. 1968), and series of cases of male breast cancer in which there has been systematic screening for sex chromatin have been reported (Table 1). In Denmark 30 patients with male breast carcinoma have been screened for sex chromatin, and the results are reported below.
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Conference proceedings 1984 we re­ peatedly attempted to identify it. We should have encountered it at least occa­ sionally in our 10 years working in the Munich hospitals with their more than 4000 beds. It was this imbalance between the allegedly relative frequency of this condition and its rare detection which led us to pla
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