Titlebook: Klinefelter’s Syndrome; Hans-Jürgen Bandmann,Reinhardt Breit,Elmar Perwein Conference proceedings 1984 Springer-Verlag Berlin Heidelberg 1

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GENUS

,Incidence of Klinefelter’s Syndrome,1983). The most frequent chromosomal aberration is Klinefelter’s syndrome, which is associated with small, solid testes with hyalinized tubules, missing spermatogenesis, and infertility. The only possible therapy is substitution.

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,Genetics and Cytogenetics of Klinefelter’s Syndrome,m, and increased excretion of follicle-stimulating hormone”. Although Ber-blinger had described a combination of similar clinical symptoms some years previously (1934), Klinefelter et al. were the first to define out of the large and heterogeneous group of primary male hypogonadism a syndrome whose

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摘要

,The Clinical Appearance of Klinefelter’s Syndrome,me. Category 1 comprises those clinical symptoms invariably present in KS, while category 2 comprises clinical symptoms which may or may not be present. Category 1 in fact contains only one symptom, namely small testicular size. Several clinical symptoms belong to category 2, e.g. gynecomastia, skel

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TOXIN

,Functional Characteristics of the Hypothalamic-Pituitary Unit in Klinefelter’s Syndrome (Pituitary in this syndrome. It has been shown that patients presented a decreased thyrotropin (TSH) response to thyrotropin-releasing hormone (TRH), while prolactin (PRL) response to the same agent was somewhat increased (Smals et al. 1977; Burman et al. 1975). In Klinefelter patients suppression of the elev

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,Taurodontism in Klinefelter’s Syndrome,eeth in which the body of the tooth is increased at the expense of the roots, as regularly seen in cattle, the teeth characteristically have a prismatic shape (Heider and Wedl 1869). Such taurodont teeth (., .) were common among Neanderthal men (Scholz and Rossiwall 1981) but can be considered quite

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,Dermatoglyphics of Klinefelter’s Syndrome,pending upon the nature and number of sex chromosomes, and clearly emerge when a large number of cases of the same kind are evaluated. One clinical condition in which there is a sex chromosome anomaly is Klinefelter’s syndrome. The karyotype most commonly associated with this condition is 47,XXY. Fo