Titlebook: Kleist-Jahrbuch 2016; Günter Blamberger,Ingo Breuer,Klaus Müller-Salget Book 2016 Springer-Verlag GmbH Deutschland 2016 Literaturgeschicht

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Balancen des Rechts lange und widersprüchliche Interpretationsgeschichte des ›Zerbrochnen Krugs‹ fordert zu immer neuen Lesarten heraus, deren theatrale Transformationen die Unordnung der Dinge und die vielfach verzerrten Figurationen der Rede und Gegenrede szenisch wahrnehmbar machen. Dass auch dieser Text Kleists ni

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mation needed to increase yield and quality and add resistance to pests, diseases and adverse environmental factors such as drought, temperature extremes and toxic soils. In the industrialized countries genetic resources are maintained and evaluated in collections supported by public funds. The Cons

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虚弱的神经

Günter Blambergerctive approach for gene therapy. Small DNA fragments (SDFs) were used in SFHR to modify endogenous genomic DNA in both human and murine cells. The advantage of this gene targeting approach is to maintain the physiologic expression pattern of targeted genes without altering the regulatory sequences (

companion

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Monika Rinckication for the treatment of many disorders. Among those, Duchenne muscular dystrophy (DMD) represents an ideal candidate for gene editing primarily due to the large size of dystrophin, the gene responsible for the disease, which limits the use of gene replacement approaches. Critical in the evaluat

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d defense mechanism in bacteria and archaea that uses short RNAs to direct degradation of foreign genetic elements. Here, we present our protocol for utilizing the . type II bacterial CRISPR system to achieve sequence-specific genome alterations in human cells. In principle, any genomic sequence of

Condescending

Andrea Bartld and programmed manner inside cells. In this regard, a new concept of reduction-controlled hierarchical unpacking is proposed for developing a virus-mimicking gene delivery system. This protocol describes the fabrications of the reduction-controlled hierarchical unpacking terplexes based on the dis

insipid

Sandra Kluwere are certain barriers in translating gene-based therapy to the clinical setting. For example, systemic delivery of genes into the brain is prevented by the blood–brain barrier (BBB); intraventricular delivery results in nonspecific distribution and gene expression; and stereotactic injection of ve

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Christiane Arndtnal cord injury and neural repair indicate that the two main obstacles that prevent successful axonal regeneration and functional recovery are the weak intrinsic regenerative capacity of the neurons and the presence of several types of inhibitory molecules in the central nervous system (CNS). Variou