| 书目名称 | Kinase Screening and Profiling |
| 副标题 | Methods and Protocol |
| 编辑 | Hicham Zegzouti,Said A. Goueli |
| 视频video | |
| 概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts |
| 丛书名称 | Methods in Molecular Biology |
| 图书封面 |  |
| 描述 | .This volume focuses on screening and profiling kinase inhibitors or activators. Chapters in this book cover several facets of the drug discovery processes starting with target identification, and assay development and screening chemical libraries for hit identification and lead optimization. The profiling portion of .Kinase Screening and Profiling: Methods and Protocols. discusses several strategies and techniques that are required to minimize off target hits and reduce cellular toxicities that are caused by liability kinases. Written in the highly successful .Methods in Molecular Biology .series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls..Timely and authoritative, .Kinase Screening and Profiling: Methods and Protocols, .will benefit scientists and researchers who are interested in exploring the role of kinases in academic, as well as pharmaceutical research.. |
| 出版日期 | Book 2016 |
| 关键词 | ATP competitive inhibitors; assay development; cellular differentiation; cellular growth; cellular toxic |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4939-3073-9 |
| isbn_softcover | 978-1-4939-4923-6 |
| isbn_ebook | 978-1-4939-3073-9Series ISSN 1064-3745 Series E-ISSN 1940-6029 |
| issn_series | 1064-3745 |
| copyright | Springer Science+Business Media New York 2016 |
发表于 2025-3-21 16:44:45
