Titlebook: Kidney Transplantation in Sensitized Patients; Duck Jong Han Book 2020 Springer Nature Singapore Pte Ltd. 2020 kidney transplantation.anti

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Preoperative Evaluation of Sensitized Patients,one effect can happen. Other kinds of solid phase assays, such as C1q SAB assay and C3d assay, are used to detect HLA antibodies, which can activate complement cascade. These HLA antibody assays should be interpreted in a comprehensive way.

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Postoperative Management,t increased in ABO-incompatible and HLA-sensitized kidney transplantation after modification of immunosuppressive protocol with reducing immunosuppression (Baek et al., BMC Nephrol. 16:201, 2015). In a recent meta-analysis study (de Weerd and Betjes. Clin J Am Soc Nephrol 13:1234–43, 2018), severe n

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Complication from Desensitization,sensitization procedure. Desensitization procedures may be undertaken to increase access to either living or deceased donor transplants, and in some situations may also be employed to facilitate participation in a kidney exchange, in less immunological barrier to be overcome. The question of whether

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Treatment of Rejection in Desensitized KT Patients,pheresis and intravenous immunoglobulin (IVIG) are known to be helpful, but there is no defined protocol. Rituximab or bortezomib have been used to inhibit the production of antibody-producing plasma cells or B cells, but have not yet shown good results, and eculizumab, c1 esterase inhibitor, and Ig

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Postoperative Results,ue to prolonged dialysis. For these reasons, most studies suggest that long-term survival of HLA-incompatible KT appears to be lower than that of compatible KT. However, it is important to point out that the choice for many of the HLA-incompatible KT patients is not between an incompatible and compa

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Book 2020y Transplantation in Sensitized Patients will assist in achieving optimal results in individual patients. It will be an important resource for everyone involved in the care of kidney transplant recipients..