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Titlebook: Isolation, Characterization and Utilization of CNS Stem Cells; F. H. Gage,Y. Christen Conference proceedings 1997 Springer-Verlag Berlin H

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Segregation of Cell Lineages in the Avian Neural Crest,ticity of neural crest cell fate was originally demonstrated through the use of avian inter-specific chimeras. Acquisition of a given phenotype in the peripheral nervous system is thus controlled by the local environments that neural crest-derived cells encounter during their migration and at their
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Comparative Strategies of Subependymal Neurogenesis in the Adult Forebrain,dents and humans. These cells reside within the peri-ventricular ependymal/subependymal zone (SZ), rather than the brain parenchyma. In vivo, these precursors may generate neurons that are recruited to restricted regions, such as the avian neostriatum and mammalian olfactory bulb. In the neurogenic
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The Oligodendrocyte-Type-2 Astrocyte Lineage: In vitro and in vivo Studies on Development, Tissue Rof the body. This challenge contains many distinct components, one of which is the deciphering of the rules that govern the behavior of precursor cells that will eventually give rise to the many cell types of the organism. This component can itself be separated into the study of precursor cells with
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Neurogenesis in the Adult Brain: Lessons Learned from the Studies of Progenitor Cells from the Embre other end a rare, self-sustaining population of stem cells that have the ability to give rise to all the cells of the central nervous system (CNS). In between these two extremes are cells termed progenitor cells, which are functionally immature and retain a limited proliferative capacity (Fig. 1).
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Use of Conditionally Immortalized Neural Progenitors for Transplantation and Gene Transfer to the Cthus used as carriers for transgenes that endow the grafted cells with properties that may be of therapeutic value. Initial studies along these lines have used genetically engineered fibroblasts (Fisher et al. 1991; Kawaja and Gage 1991; Kawaja et al. 1992; Dekker et al. 1994) or muscle cells (Jiao
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The Origins of the Central Nervous System,e assembly of a multicellular system. Second, this knowledge will permit us to control the assembly and disassembly of this system in health and in disease. Of course the brain is an extraordinarily complex device and there are many steps in the assembly process. Following the advice given to Alice
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