Titlebook: Islets of Langerhans; Md. Shahidul Islam Living reference work 20200th edition

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Calcium Signaling in the Islets,to be learnt about the mechanisms of generation and decoding of Ca. signals, much de-learning will also be needed. Human β-cells do not have a resting state in the normal human body even under physiological fasting conditions. Their membrane potential under physiologically relevant resting condition

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,Clinical Approaches to Preserving β-Cell Function in Diabetes,agonists (GLP-1 mimetics), not inactivated by the enzyme dipeptidyl peptidase-4, and/or to inhibit that enzyme (GLP-1 enhancers). The incretin hormones are released from the gastrointestinal tract in response to nutrient ingestion to enhance glucose-dependent insulin secretion from the pancreas and

Prologue

Electrophysiology of Islet Cells,ent Na. and/or Ca. channels and repolarized by voltage- and/or Ca.-dependent K. channels. At a constant stimulatory glucose concentration, APs are clustered in bursts that are interrupted by hyperpolarized interburst phases. Bursting electrical activity induces parallel fluctuations in [Ca.]. and in

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Exercise-Induced Pancreatic Islet Adaptations in Health and Disease,ces β-cell survival is a common outcome in all of the studies. Exercise training-induced alterations on β-cell functions are more controversial. Generally, the studies indicate that in healthy and obese insulin-resistant subjects, exercise decreases nutrient-induced insulin secretion (associated wit

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,Exocytosis in Islet β-Cells, using the currently available electrophysiological techniques. This chapter provides a concise introduction to the field of optical imaging for those researchers who wish to characterize exocytosis from β-cells in the islets of Langerhans.

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,High-Fat Programming of β-Cell Dysfunction,bolism of the progeny throughout life. This more recently adopted form of developmental programming reflects society in both affluent and developing countries. High-fat programming induces adverse changes in β-cell development and function in neonatal, weanling, and adolescent progeny. These changes

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Haruo Kasai,Hiroyasu Hatakeyama,Mitsuyo Ohno,Noriko Takahashiasserkuppe über die Berge der Rhön, mit ihr promenieren am Strande Spitzbergens, dort über mächtige Gletscher hinweg auf die schwarzen scharfen Zinnen steigen, mit ihr auf Meereswellen herumspazieren, dem alten berühmten Moltke um die Nasenkuppe herumklettern, mit ihr auf einem lebenden Fische sitze