Titlebook: IschemiRs: MicroRNAs in Ischemic Stroke; From Basics to Clini Rajanikant G. K.,Pierre Gressens,Cindy Bokobza Book 2020 Springer Nature Sing

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microRNAs in Normal Brain PhysiologyAs at the post-transcriptional level. Highly conserved across species, they are known to regulate many genes in critical pathways during the lifetime. Any dysregulation at the cellular level, but also in the entire organism, is therefore harmful. The brain is a privileged organ in many ways, and int

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MicroRNAs in Ischemic Stroke Pathophysiology: Special Emphasis on Early Molecular Events differentially after an ischemic stroke. MicroRNAs control multifaceted pathophysiological events such as excitotoxicity, calcium overload, and oxidative stress within minutes of an inflammatory response and neuronal apoptosis within hours and days of the onset of the stroke. This chapter brings to

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Regulatory Role of microRNAs in Ischemic Cell Deathed injury, or trauma resulting in the death of cells. There are many cell death pathways so far reported in various kinds of literature, and many are continuously being discovered and reported having regulatory functions. Even though there are many cell death pathways activated in various diseases h

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The Emerging Role of microRNAs in Post-ischemic Angiogenesis and Neurogenesis neurodevelopment and neuropathology. microRNAs (miRNAs) regulate the generation of new neurons in the stroke-damaged adult brain to propagate post-ischemic self-repair..Similarly, a large number of individual miRNAs control endothelial cell (EC) proliferation and migration and promote vascular-netw

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MicroRNAs as Potential Diagnostic, Prognostic, and Therapeutic Biomarkers in Ischemic Strokeal value extends beyond diagnosis to therapeutic applications for better treatment outcomes. The gold standard of protein biomarkers has outlasted over decades, but a slow progression of microRNAs (miRs) as a novel biomarker has risen as of late. The unique nature of miRs has enabled them to be more