Titlebook: Irregular Migration; IMISCOE Short Reader Maurizio Ambrosini,Minke H.J. Hajer Book‘‘‘‘‘‘‘‘ 2023 The Editor(s) (if applicable) and The Autho

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Maurizio Ambrosini,Minke H. J. Hajerrials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.. .Authoritative and accessible, .Epigenetics Protocols, Second Edition. ser978-1-4939-6187-0978-1-61779-316-5Series ISSN 1064-3745 Series E-ISSN 1940-6029

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rs as well as hematologic malignancies and hemoglobinopathy.The growing knowledge about disturbances of epigenetic gene regulation in hematopoietic stem cell disorders is now being translated into treatment approaches that target the epigenetic defects pharmacologically. This book first presents the

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Maurizio Ambrosini,Minke H. J. Hajerrs as well as hematologic malignancies and hemoglobinopathy.The growing knowledge about disturbances of epigenetic gene regulation in hematopoietic stem cell disorders is now being translated into treatment approaches that target the epigenetic defects pharmacologically. This book first presents the

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Maurizio Ambrosini,Minke H. J. Hajerf organisms. This means it is able to offer a specific perspective on how various factors and stressors in the environment control gene activity. For instance, chemicals such as hormonally active ‘endocrine disruptors’ leave behind traces in the epigenetic code that not only trigger illnesses, but c

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Maurizio Ambrosini,Minke H. J. Hajer (ROS). High levels of ROS directly damage proteins, lipids, and DNA. Oxidative lesions of DNA lead to increased chromosomal breakage numbers and genomic instability. Besides, ROS induce activation of signaling cascades and regulate transcription factors, which result in changes in proliferation, an

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