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Titlebook: Iron Metabolism; Iván Bernát Book 1983 Springer Science+Business Media New York 1983 metabolism

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楼主: 面临
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Iron Transport, system (RES) and it is transported to the bone marrow for new hemoglobin synthesis. A smaller proportion of iron enters the transport pool from the gastrointestinal tract, from storage iron, and from catabolism of tissue hemins.
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Iron Loss and Iron Requirement,he differentiation between nonabsorbed iron and iron excreted through the gastrointestinal tract. Isotope techniques require knowledge of the distribution of the radioiron within the organism and the extent of the various iron pools.
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Erythropoiesis,ructural proteins). The basic information for the synthesis of specific proteins is stored in the DNA, and the mRNA conveys the message of the code to the ribosomes. The latter adhere to the long chain of the mRNA and scan the information to select in a given order the amino acids that are required for the synthesis of polypeptide chains.
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Hemoglobin Synthesis,globin consists of two alpha and two beta chains. The alpha chains comprise 141 and the beta chains 146 amino acids. The molecular weight of hemoglobin is 64,458. Under biological conditions the molecular weight is somewhat higher, 66,000 according to Drabkin.
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Overview: 978-1-4615-7310-4978-1-4615-7308-1
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Distribution and Function of the Iron-Containing Complexes of the Human Organism,The healthy human adult contains on an average 4–5 g of iron (Fig. 4/1), but individual values depend on body weight, on the total amount of the circulating hemoglobin, and on iron stores, so that the normal variation may be between 3 and 6 g.
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Storage Iron,In the normal adult male about 25–30% of the total iron content is present in iron stores, the amount depending upon the balance between iron absorption from the gut and iron loss. Because of the greater physiological requirements of women during reproductive life, their stores are usually smaller than those of men (Weinfeld, 1964).
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