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Titlebook: Iron Metabolism; Iván Bernát Book 1983 Springer Science+Business Media New York 1983 metabolism

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楼主: 面临
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Erythropoiesis,ructural proteins). The basic information for the synthesis of specific proteins is stored in the DNA, and the mRNA conveys the message of the code to the ribosomes. The latter adhere to the long chain of the mRNA and scan the information to select in a given order the amino acids that are required
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Hemoglobin Synthesis,globin consists of two alpha and two beta chains. The alpha chains comprise 141 and the beta chains 146 amino acids. The molecular weight of hemoglobin is 64,458. Under biological conditions the molecular weight is somewhat higher, 66,000 according to Drabkin.
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Erythrokinetics,erlying the various forms of anemia. In clinical practice an estimate of the total erythropoiesis is obtained by measuring the erythroid/myeloid (E/M) ratio in the bone marrow and the plasma iron transport rate, whereas effective erythropoiesis can be estimated from the iron utilization and correcte
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Iron Deficiency,oof was only provided in the 1930s. Chlorosis was ascribed to the disturbed endocrine function of the ovaries (Naegeli, 1931; and others) and the therapeutic effect of iron was believed to be through a stimulatory effect on the pathological bone marrow function that developed as a result of the endo
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Biochemical Evolution of the Heme-Type Enzymes,iving organisms that the first protoplasms to evolve must have possessed this ability (Granick, 1953). It is unlikely that the ability for oxidation would have developed only with the development of the heme molecule.
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