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Titlebook: Introduction to Evolutionary Genomics; Naruya Saitou Textbook 20131st edition Springer-Verlag London 2013 Bioinformatics.Bioinformatics.Ev

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Prokaryote Genomesuencing efforts, the basic structure of prokaryote genomes is discussed using . as an example, followed by discussions on GC content heterogeneity, horizontal gene transfer, codon usage, and plasmids. Finally, we discuss prokaryotic metagenomes.
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Vertebrate Genomesd conserved noncoding sequences. We then move to brief description of vertebrate genomes for major phylogenetic lineages: teleost fish, amphibian, and amniotes. Mammals, in which many species genomes were already sequenced, were discussed in more details.
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Human Genomee, protein coding genes, and RNA genes, are first discussed. Personal genome sequencing and genomic heterogeneity are described next. We then discuss genetic changes to produce humanness. At the end, ancient human genomes are briefly reviewed.
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Evolutionary Distances substitutions including one-parameter method, two-parameter method, and methods incorporating observed nucleotide frequencies were explained in detail. Methods for estimating synonymous and nonsynonymous substitutions and amino acid substitutions were also discussed.
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Tree and Network Buildinglassification of tree-building methods, both by type of data and by type of tree search algorithm. Various distance matrix methods including UPGMA, minimum deviation methods, minimum evolution methods, transformed distance methods, and neighbor-joining method are explained. Among character-state met
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