书目名称 | Intracellular Signal Transduction: The JAK-STAT Pathway |
编辑 | Andrew F. Wilks,Ailsa G. Harpur |
视频video | |
丛书名称 | Molecular Biology Intelligence Unit |
图书封面 |  |
描述 | This book is the first one written about the JAK/STAT pathway. The JAK (Janus Kinase) Protein tyrosine kinases are novel phosphotransferases absolutely required for cellular signalling downstream of non-catalytic cytokine receptors (amongst others). These molecules are components in pathways utilising the STAT (Signal Transducers and Activators of Transcription) transcription factors. The basic components of the JAK/STAT pathway are covered in detail, and the centre piece of the book is a guided tour of the pathway itself. An interesting addition to the book is the chapter on the use of Drosophila melanogaster as a genetic system to probe the pathway at the whole organism level. The book is targeted to researchers who have an interest in intracellular signalling. |
出版日期 | Book 1996 |
关键词 | Drosophila; cytokine; protein; receptor; signal transduction; transcription |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-662-22050-4 |
isbn_softcover | 978-3-662-22052-8 |
isbn_ebook | 978-3-662-22050-4Series ISSN 1431-0414 |
issn_series | 1431-0414 |
copyright | Springer-Verlag Berlin Heidelberg 1996 |