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Titlebook: Intracellular Cholesterol Trafficking; T. Y. Chang,Dale A. Freeman Book 1998 Springer Science+Business Media New York 1998 cell.macrophage

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Mechanisms and Consequences of Cholesterol Loading in Macrophagesm cell formation. Macrophage foam cells form by the internalization and metabolism of “atherogenic” lipoproteins that accumulate on the subendothelial matrix. Among the most potent inducers of foam cells are aggregated LDL and chylomicron remnants. Cholesterol molecules from these lipoproteins are e
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Direct Evidence for Sterol Carrier Protein-2 (SCP-2) Participation in ACTH Stimulated Steroidogenesidrenocorticotropic hormone (ACTH). The steroidogenic response (measured as corticosterone production) of these cells was inhibited by 45–60%, compared to cells fused with liposomally entrapped non-immune IgG or buffer. Furthermore, the degree of inhibition was shown to be dependent on the amount of
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Scavenger Receptors, Caveolae, Caveolin, and Cholesterol Traffickingnism of selective uptake can be divided into three components: 1) association of HDL with the plasma membrane, 2) transport of cholesterol esters from HDL to the plasma membrane, and 3) trafficking of the cholesterol esters from the plasma membrane to the endoplasmic reticulum. A recent convergence
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Selective Uptake of Lipoprotein Free Cholesterol and Its Intracellular Transport — Role of Caveolinay regulates cholesterogenesis. and promotes FC efflux via its effect on the transcriptional regulation of caveolin, the major structural protein of caveolae. Caveolae are the terminus at the cell surface of both newly synthesized FC and FC recycled from LDL. Caveolar FC is effectively transferred t
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Ta-Yuan Chang,Catherine C. Y. Chang,Oneil Lee.. The kinetics of concentration polarization is a rate-controlling electrochemical process since the electrode is cathodically polarized. The mass transfer may be by diffusion, migration, convection or a combination of these modes. Thus, the Nernst-Plank equation can give reasonable results. Howeve
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Peter Oelkers,Stephen L. Sturley,Arthur Tinkelenberguxiliary electrode, such as the tip of a scanning tunneling microscope, is employed, there are even two potential drops that can be controlled individually: the bias potential between the two electrodes and the potential of one electrode with respect to the reference electrode. Thus, electrochemistr
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