Titlebook: Interleukin 12: Antitumor Activity and Immunotherapeutic Potential in Oncology; Witold Lasek,Radoslaw Zagozdzon Book 2016 The Author(s) 20

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Antitumor Effects of IL-12 in Preclinical Studies,Immunother 63: 419–435, .). To further attenuate IL-12-induced toxicities, in many recent preclinical treatment schemes, gene therapy approaches have been tested in which the IL-12 gene is introduced in various viral and non-viral vectors. Some of these approaches have been and are being applied in

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Clinical Trials with IL-12 in Cancer Immunotherapy,on induced severe side effects. In fact, only few studies reported promising results with sporadic overt tumor regressions (apart from patients with AIDS-associated Kaposi sarcoma). Due to the low response to IL-12 and its high toxicity, accrual to some trials was even stopped (Motzer et al. in Jour

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Interleukin 12: Antitumor Activity and Immunotherapeutic Potential in Oncology

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Witold Lasek,Radoslaw ZagozdzonExplores the biology of interleukin 12 and its potential in cancer therapy.Discusses antitumor effects identified in preclinical studies and clinical trials in cancer immunotherapy.Is particularly rel

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SpringerBriefs in Immunologyhttp://image.papertrans.cn/i/image/471136.jpg

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Andrew Kwok-Fai Lui,Sin-Chun Ng,Yin-Chun Fungame time, but the number of users is limited by the multiuser interference (MUI) (see, e.g. [54]) due to the fact that the spread spectrum codes are not orthogonal. In real systems, not only the number of users increases the MUI but we also have to deal with the relative distances of them from the r