| 书目名称 | Inhibitors of Nucleic Acid Synthesis |
| 副标题 | Biophysical and Bioc |
| 编辑 | Helga Kersten,Walter Kersten |
| 视频video | |
| 丛书名称 | Molecular Biology, Biochemistry and Biophysics‘ Molekularbiologie, Biochemie und Biophysik |
| 图书封面 |  |
| 描述 | During the last decade physical and chemical methods have improved rapidly - a fact which allowed the mode of action of antibiotics to be studied - and many biochemically-oriented scientists have devoted their research to the following questions: 1. What is the metabolic pathway that is inhibited selectively, and what are the target molecules within a sensitive cell? 2. What are the relationships between the chemical structure of an antibiotic and the physicochemical properties of the sensitive mole cule(s)? 3. Why and how far is the action selective? 4. Is it possible to correlate the interaction with the target mole cule(s) with the particular biological activities observed? This monograph deals with those antibiotics which interfere with the biosynthesis of nucleic acids. The idea was to provide an insight into how to investigate the preceding questions experimentally and to solve as yet unresolved problems rather than to give a review of the current state of knowledge. Although the biochemistry of nucleic acid synthesis is known in general, the precise molecular mechanisms by which deoxyribonucleic acid is replicated or transcribed has still to be clarified. For this reason i |
| 出版日期 | Book 1974 |
| 关键词 | Antibiotikum; Antimetabolit; Biosynthese; Nukleinsäure; biochemistry; chemistry; protein; transcription; tra |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-642-80855-5 |
| isbn_softcover | 978-3-642-80857-9 |
| isbn_ebook | 978-3-642-80855-5Series ISSN 0077-0221 |
| issn_series | 0077-0221 |
| copyright | Springer-Verlag Berlin Heidelberg 1974 |
发表于 2025-3-21 20:08:22
