Titlebook: Information- and Communication Theory in Molecular Biology; Martin Bossert Book 2018 Springer International Publishing AG 2018 Cell-cell c

讥讽

MicroRNA as an Integral Part of Cell Communication: Regularized Target Prediction and Network Predic (iii) application of the Infomax approach to guarantee minimal loss of information after dimension reduction, and (iv) experimental validation of theoretical predictions using a novel test system. This strategy will allow (i) statistical analysis of the predicted microRNA–mRNA hypergraph, (ii) char

blight

Highbrow

Information Theoretic Concepts to Unravel Cell–Cell Communicationresponse time series as well as changes in the whole secretome to correlate cytokine patterns with phenotype responses. Moreover, we model the changes in gene expression and cytokine secretion through communication theoretic approaches through independent component analysis and Gaussian processes. T

难理解

Finding New Overlapping Genes and Their Theory (FOG Theory)in order to transmit information reliably over channels which introduce errors. Evolution, as well as the process of coding proteins by overlapping genes, can be viewed as such a communication system. Both will be described and analyzed with the theory from communication systems, including synchroni

涂掉

尽管

Improving the Reliability of RNA-seq: Approaching Single-Cell Transcriptomics To Explore Individualimprehensive channel model of RNA-seq using statistical analysis and suitable experiments. The new established sequencing procedure will then be used to explore the stochastic cell-to-cell variability of transcriptomic profiles. We are especially interested in the phenomena of stochastic cell-state s

dearth

Evolution of the AMP-Activated Protein Kinase Controlled Gene Regulatory Networking algorithms for extended Context Tree Maximization (CTM) and extended Parsimonious Context Tree Maximization (PCTM) are derived, implemented, and applied. Computational predictions and experimental validation will establish an iterative cycle to improve algorithms in each cycle leading to a growi

工作

不朽中国

Information Transfer in the Mammalian Circadian Clockfor the responses? To address these questions, we combine experimental data from cultured single cells and organotypic slices with mathematical models of circadian oscillators and find that temperature signals have a strong impact on circadian rhythms, depending on the specific circadian properties

斗志

The DNA from a Coding Perspectiveal and analog) types of information and on the biological meaning of this capacity. In particular, the interdependence of digital and analog coding properties of the DNA is studied with regard to regulation of genetic function. To this end, the role of the spatial order of genes and the genomic grad