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Titlebook: Influenza Virus Sialidase - A Drug Discovery Target; Mark Itzstein Book 2012 Springer Basel AG 2012 Avian influenza.Drug design.Infectious

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The Development of Non-Carbohydrate-Based Influenza Virus Sialidase Inhibitors,
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Clinical Experience with Influenza Virus Sialidase Inhibitors,
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Influenza Virus Sialidase - A Drug Discovery Target
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Book 2012ign, synthesis and evaluation of carbohydrate as well as non-carbohydrate influenza virus sialidase inhibitors. Further reviews of the clinical experience with influenza virus sialidase inhibitors and of the development of resistance to these inhibitor drugs complement the topic..
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Book 2012 with the recent emergence of the influenza virus A/H1N1 pandemic. The development of new anti-influenza drugs is thus a major challenge. .This volume describes all aspects of the virus structure and function relevant to infection. The focus is on drug discovery of inhibitors to the enzyme sialidase
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Multi-material Phase Field Approach to Structural Topology Optimization the relation of the necessary conditions to classical shape derivatives are discussed. An efficient numerical method based on an ..–gradient projection method is introduced and finally several numerical results demonstrate the applicability of the approach.
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