Titlebook: Influenza Vaccines for the Future; Rino Rappuoli,Giuseppe Giudice Book 20081st edition Birkhäuser Basel 2008 Influenza.avian influenza.bio

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Influenza virus: The biology of a changing virus,za virus types A, B, and C. This introduction provides a detailed overview of influenza virus classification, structure, and life cycle. We also include a brief review of the clinical manifestations of influenza and the molecular determinants for virulence. The genetic diversity of influenza A virus

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itinerary

The epidemiology of influenza and its control,pidemiology has benefited greatly from analysis of large data sets regarding hospitalization, mortality, and outpatient visits. These data have allowed comparison of the impact of influenza in various climates and the evaluation of the direct and indirect benefits of vaccination, the latter through

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Influenza and influenza vaccination in children, outpatient settings. Mortality and encephalitis due to influenza have also been reported. Two vaccines are licensed for use in children; trivalent inactivated and live attenuated vaccines. Both have been shown to be efficacious for the prevention of clinically and laboratory-confirmed influenza. In

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Live attenuated influenza vaccine,ed influenza A strains and one attenuated influenza B strain; these vaccine strains are genetic reassortants each harboring two gene segments from the wild type virus conferring the appropriate antigens (e.g. A/H3N2, A/H1N1 or B) and the remaining 6 gene segments of the live, attenuated influenza A

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