Titlebook: Inflammation-Associated Depression: Evidence, Mechanisms and Implications; Robert Dantzer,Lucile Capuron Book 2017 Springer International

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Mechanisms of Inflammation-Associated Depression: Immune Influences on Tryptophan and Phenylalanine, most importantly of tryptophan and phenylalanine, plays a central role. In addition, neuropsychiatric conditions that go along with disorders that are characterized by acute or chronic inflammation, such as the development of depression, decreased quality of life or cognitive impairments, are conn

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Depression in Autoimmune Diseases,ystem not only leads to inflammation in affected organs, but also mediates behavior abnormalities including fatigue and depression-like symptoms. This review focuses on the different pathways involved in the communication of the immune system with the neuronal network and the body’s timing system. T

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The Role of Dopamine in Inflammation-Associated Depression: Mechanisms and Therapeutic Implicationscytokines affect the basal ganglia and dopamine to mediate depressive symptoms related to motivation and motor activity. Findings have included inflammation-associated reductions in ventral striatal responses to hedonic reward, decreased dopamine and dopamine metabolites in cerebrospinal fluid, and

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Role of Kynurenine Metabolism Pathway Activation in Major Depressive Disorders,ory processes may play a causal role in the developmental of depressive illness. While there may be multiple causal pathways through which inflammatory processes affect mood, activation of the kynurenine pathway is essential for the development of depression-like behavior in rodents. Studies of hepa

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Suicidality and Activation of the Kynurenine Pathway of Tryptophan Metabolism,s calculated to be the 14th leading cause of death around the world. While the biological mechanisms causing suicidal ideation and behavior are not fully understood, increased levels of inflammation, arising from various sources, have been detected in the central nervous system and the peripheral bl

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