书目名称 | Inflammation and Metastasis | 编辑 | Yoshiro Maru | 视频video | | 概述 | Explains the concept of homeostatic inflammation and explores the significance of its dysregulation for metastasis.Presents new information from multiple research fields.Discusses novel potential ther | 图书封面 |  | 描述 | .This book, now in a thoroughly revised and updated second edition, provides the latest information on cancer metastasis from the perspective of inflammation and presents new ideas on the complicated mechanisms of metastasis and potential therapeutic targets. Key features include discussion of mechanisms recently identified to be involved in the resolution phase of inflammation, presentation of the latest evidence regarding the roles of endogenous TLR4 ligands in metastasis, and thorough explanation of the concept of homeostatic inflammation and current understanding of the significance of its dysregulation for metastasis. Structure-based thinking is another important element of the book, and it is proposed that inflammation forms a functional triangle with angiogenesis and coagulation, at the center of which cancer is located. Examples of the many additional specific topics covered in this edition include the functional involvement of new types of RNA in cancer, the insights offered by recent advances in bioinformatics, and the potential of a casein kinase 1α inhibitor in the treatment of acute myeloid leukemia. The book will be a valuable update and resource for both experienced | 出版日期 | Book 2021Latest edition | 关键词 | Inflammation; Metastasis; Leukocytes; Microenvironment; Pathogen sensors; Immune system; Coagulation; Angio | 版次 | 2 | doi | https://doi.org/10.1007/978-981-16-1757-7 | isbn_softcover | 978-981-16-1759-1 | isbn_ebook | 978-981-16-1757-7 | copyright | Springer Nature Singapore Pte Ltd. 2021 |
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