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Titlebook: Inflammation; John R. Vane,Sergio H. Ferreira Book 1978 Springer-Verlag Berlin Heidelberg 1978 Chemokine.Histamin.Hypothalamus.Insulin.Nic

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A Brief History of Inflammationscription of the phenomenon was presented by Celsus, a Roman physician of the 1 st century A.D., who described the classic signs of inflammation: . (redness), . (swelling), with . (heat) and . (pain). However, formation of pus with heat, redness and pain are characteristic of the phenomenon as it de
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The Adhesion, Locomotion, and Chemotaxis of Leucocytesells to the vascular endothelium, particularly in postcapillary venules; migration of adherent leucocytes between the endothelial cells and out of the vessel; detachment of the cells and their subsequent homing onto the site of injury (see ., Chapter 2, this volume). These events require two fundame
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Platelet Aggregation Mechanisms and Their Implications in Haemostasis and Inflammatory Diseasevailable and can be isolated free from other cell types. Biochemical studies of the platelet have taught us a great deal about amine uptake, storage, and release, lysosomal enzymes, contractile proteins, and the biological significance of cyclic nucleotides. Furthermore, study of the factors involve
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Regeneration and Repairurious agent itself upon the living cells in its vicinity, e.g. the dermo-necrotic factor of staphylococci, or indirectly from ischaemia as a consequence of local vascular stasis or thrombosis. The replacement of the necrotic tissue by a living tissue requires two preconditions: the removal of the n
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The Release of Hydrolytic Enzymes From Phagocytic and Other Cells Participating in Acute and Chronicath of cells after interaction with cytotoxic agents or in a selective manner, where hydrolase release occurs by secretion from viable cells. The latter process has attracted much attention in recent years since it constitutes a mechanism by which hydrolytic enzymes can be released in a directed man
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Lysosomal Enzymeshe biochemist’s analysis of the isolated organelles and their molecular components. The pattern was reversed for lysosomes, the nature and function of which were not recognized until they had been characterized chemically. The discovery of lysosomes began in 1949 by Dr. . and his colleagues, with an
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Lymphokinesd the delay in onset of skin reactions evoked in animals sensitized by intracellular parasites as compared with the relatively rapid response to antigen in animals sensitized by intradermal administration of protein antigen. An experimental basis for this distinction was provided by . and . (1942),
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