Titlebook: Inducible Enzymes in the Inflammatory Response; Derek A. Willoughby,Annette Tomlinson Book 1999 Springer Basel AG 1999 clinic.enzyme.infla

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Inducible nitric oxide synthase and inflammation,ble advances in the understanding of the role of nitric oxide (NO) as an inter- and intra- cellular messenger molecule have also established that NO plays an important role as a mediator of inflammation.

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Affluence

Role of the inducible forms of cyclooxygenase and nitric oxide synthase in inflammatory pain,s are not active in normal tissues, but are “switched on” during inflammation. This functional upregulation leads to a clinical state known as hyperalgesia. In such a situation, previously unpainful stimuli become painful.

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Inducible enzymes In the pathogenesis of rheumatoid arthritis,nsiderable financial burden on national economies. Intervention therapy tends merely to limit inflammation and may induce adverse reactions but, in general, there is little effect on disease progression, possibly highlighting our misconception of the disease process. To this end, novel therapeutic targets are essential.

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