书目名称 | Increasing the Therapeutic Ratio of Radiotherapy |
编辑 | Philip J. Tofilon,Kevin Camphausen |
视频video | |
概述 | Focuses on potential targets/strategies for increasing the therapeutic ratio for radiotherapy.Discusses radiotherapies with an integrated approach.Highlights advances in approaches as well as the barr |
丛书名称 | Cancer Drug Discovery and Development |
图书封面 |  |
描述 | Current cancer therapies are focused on three general strategies: modifying intrinsic radiosensitivity via molecular targeting, manipulating microenvironmental factors to enhance tumor susceptibility to radiation, and improving delivery of radiation to critical tumor locations while sparing normal tissues. The goal of this volume is to describe a number of promising approaches corresponding to each strategy..In general, research in radiation oncology tends to be siloed into fundamental biology, physics or treatment delivery. The strategies for improving therapeutic ratio encompassed in this book will involve each of these components of radiation oncology. Thus, they will illustrate the variety of disparate approaches available for potentially improving the efficacy of radiotherapy, which may then stimulate discussion across disciplines and foster further translational investigations..Although a goal of each chapter will be to highlight advances within an approach, of equal importance will be the delineation of barriers to successful clinical application and how to overcome or minimize such impediments. Along these lines, because therapeutic ratio incorporates both tumor and normal |
出版日期 | Book 2017 |
关键词 | DNA; DNA repair; Radiotherapy; Therapeutic Ratio; Tumors; Radiaton Oncology; antibacterial drug resistance |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-319-40854-5 |
isbn_softcover | 978-3-319-82201-3 |
isbn_ebook | 978-3-319-40854-5Series ISSN 2196-9906 Series E-ISSN 2196-9914 |
issn_series | 2196-9906 |
copyright | Springer International Publishing Switzerland 2017 |