书目名称 | In Vitro Toxicology Systems | 编辑 | Anna Bal-Price,Paul Jennings | 视频video | | 概述 | Addresses toxicity testing, in vitro, in a variety of different human system simulations.Features difficult areas of toxicology such as carcinogenicity and nanotoxicology.Benefits students and experts | 丛书名称 | Methods in Pharmacology and Toxicology | 图书封面 |  | 描述 | .In Vitro Toxicology Systems. brings together important issues and considerations needed in order to develop a workable, reliable, integrated testing strategy for the replacement of animals in toxicity testing regimes. This thorough volume includes sections on in vitro models for systemic organ toxicity, neurotoxicity, sensory organs, immunotoxicity and reproductive toxicity and addresses how stem cells may be used going forward. The book also tackles difficult areas of toxicology such as carcinogenicity and nanotoxicology, with additional chapters dedicated to kinetics, metabolism, and in vitro in vivo extrapolation. The book also addresses biological processes such as stress response pathways and mechanistic biomarkers and how these can be uncovered and measured using high content approaches..Reliable and authoritative, .In Vitro Toxicology Systems. will be of benefit not only to students, scientists and regulators working in the field of chemical safety assessment but also to a wider scientific audience.. | 出版日期 | Book 2014 | 关键词 | Cell culture; Chemical testing; Drug safety assessment; Human toxicity prediction; Pharmaceuticals; Predi | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4939-0521-8 | isbn_softcover | 978-1-4939-5480-3 | isbn_ebook | 978-1-4939-0521-8Series ISSN 1557-2153 Series E-ISSN 1940-6053 | issn_series | 1557-2153 | copyright | Springer Science+Business Media New York 2014 |
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