书目名称 | In Silico Models for Drug Discovery | 编辑 | Sandhya Kortagere | 视频video | | 概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts.Includes supplementary materia | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | .Infectious diseases caused by viruses, parasites, bacteria, and fungi are the number one cause of death worldwide. Although new technologies have improved diagnosis of infectious diseases, the efficacy of all known current anti-infective agents is threatened by the spread of drug-resistant forms of the pathogens. Hence, there remains an urgent need to develop anti-infective agents that target drug-resistant pathogens.. In Silico Models for Drug Discovery. presents a comprehensive look at the role .in silico .models play in understanding infectious diseases and in developing novel therapeutics to treat them. Written by leading experts in the field, chapters cover topics such as techniques to derive novel antimicrobial targets, methods of interpreting polypharmacology-based drug target networks, and molecular dynamics techniques used to compute binding energies of drugs to their target proteins, to name a few. Written in the successful .Methods in Molecular Biology™. series or in review article format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting an | 出版日期 | Book 2013 | 关键词 | antimicrobial targets; drug design; drug discovery; drug resistance; novel inhibitors | 版次 | 1 | doi | https://doi.org/10.1007/978-1-62703-342-8 | isbn_softcover | 978-1-4939-6297-6 | isbn_ebook | 978-1-62703-342-8Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Springer Science+Business Media, LLC 2013 |
The information of publication is updating
|
|