Titlebook: Immunoneurology; Michel Chofflon,Lawrence Steinman Book 1996 Springer-Verlag Berlin Heidelberg 1996 Guillian Barr syndrom.cytokine.cytokin

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Multiple sclerosis: a unique immunopathological syndrome of the central nervous system,at the immune system is crucial in the pathogenesis of the recurrent and chronic injury to the central nervous system (CNS). Nearly identical histopathological findings occur in MS and related clinical syndromes, designated as “demyelinating diseases.” Clinical presentation differentiates MS from th

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Experimental immunotherapies for multiple sclerosis,gy is as yet unknown current evidence suggests that tissue damage is mediated by autoimmune T cells. The examination of an experimental animal model for MS, experimental allergic encephalomyelitis (EAE), has demonstrated that myelin basic protein (MBP)- or proteolipid protein (PLP)-specific T cells

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Superantigens in demyelinating disease,latory mechanisms control T and B cell tolerance to self antigens. While genetic factors influence susceptibility to autoimmunity in humans and experimental animals, environmental factors contribute to disease penetration. For autoimmune disease to occur, autoreactive lymphocytes have to be activate