书目名称 | Immunoglobulins | 编辑 | Gary W. Litman,Robert A. Good | 视频video | | 丛书名称 | Comprehensive Immunology | 图书封面 |  | 描述 | Since the discovery more than thirty years ago that antibody actlvlty could be localized to discrete plasma protein fractions, the study of immunoglobulin struc ture and function has dominated the field of immunochemistry. During this time, sources of homogeneous immunoglobulin molecules have been discovered, the subunit nature of the proteins has been defined, and the three-dimensional struc tures of the antigen-recognition portion of several antibody molecules have been elucidated. Insights into the complicated genetic control of these proteins are being gained rapidly through analysis of amino acid sequences of naturally occurring and induced homogeneous immunoglobulins. Immunoglobulins have been analyzed by protein chemists as models of complex multimeric systems, examined by geneticists studying serum protein polymorphisms, and employed by molecular biologists as highly selective probes capable of distinguishing minor features of molecular topog raphy. Clinical applications have ranged from the now routine quantitation of immunoglobulin levels to the use of antibodies to detect trace levels of a variety of natural products and drug metabolites. All these applications have d | 出版日期 | Book 1978 | 关键词 | antibody; antigen; immunoglobulin; proteins | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4684-0805-8 | isbn_softcover | 978-1-4684-0807-2 | isbn_ebook | 978-1-4684-0805-8 | copyright | Plenum Publishing Corporation 1978 |
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