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Titlebook: Immunogenicity of Biopharmaceuticals; Marco van de Weert,Eva Horn Møller Book 2008 Springer-Verlag New York 2008 Biosimilar.drug.interfero

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an overview of the immune system and factors that may trigger the immune system, via detection of antibodies and clinical implications, to various case examples and the regulatory view on immunogenicity. .978-1-4419-2608-1978-0-387-75841-1
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Case Study: Immunogenicity of Interferon-Beta,quired for optimal and individualized therapies, and Ab detection induced during therapy. In an effort to assess the clinical relevance of in vitro Ab measurements, many investigators distinguish between ‘binding’ Abs (BAbs) and in vitro ‘neutralizing’ Abs (NAbs) even though such a distinction may n
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,Immune Reactions Towards Biopharmaceuticals – a General, Mechanistic Overview,
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Immunogenicity of Biopharmaceuticals: Causes, Methods to Reduce Immunogenicity, and Biosimilars,
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