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Titlebook: Immuno-Oncology; Cellular and Transla Seng-Lai Tan Book 2020 Springer Science+Business Media, LLC, part of Springer Nature 2020 Cancer immu

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In Vitro Functional Assay Using Real-Time Cell Analysis for Assessing Cancer Immunotherapeutic Agenl-time manner. This specialized microtiter plate system uses integrated gold microelectrodes as a sensor to measure the electronic current flow that is impeded by the tumor cells attached on the sensor surface. This measured impedance signal is dictated by cell number, size, and surface attachment s
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Induction and Potential Reversal of a T Cell Exhaustion-Like State: In Vitro Potency Assay for Function to persistent antigen exposure, TILs within the TME encounter numerous tumor-mediated immunosuppressive metabolic by-products, suppressive cytokines, hypoxia, and cellular debris which converge to suppress T cell function and uniquely alter its transcription factor profile. These suppressed or
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Miniaturized Single Cell Imaging for Developing Immuno-Oncology Combinational Therapies,nt, enabling screening of up to 50 drug conditions per one million primary cells. This approach also employs the capability to perform digitized molecular counting to quantify surface and intracellular . This miniaturized single cell imaging approach offers new capabilities for assessing the functio
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The Quest for the Next-Generation of Tumor Targets: Discovery and Prioritization in the Genomics Erhe general low affinity of T-cell receptors (TCRs) for self-antigens..Recent efforts have, therefore, been directed towards the discovery and validation of neoantigens, that arise from mutations in cancer cells. Emerging alternatives to neoantigens are mutational hotspot antigens and cancer-specific
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Min Dai,Ingegerd Hellstrom,Karl Erik Hellstromship between civilizational populism, democracy and national.This edited book examines the growing worldwide phenomenon of civilizational populism in democratic nation-states and brings together research that explores this in a wide variety of religious, political, and geographic contexts. In doing
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