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Titlebook: Immunization Against Alzheimer’s Disease and Other Neurodegenerative Disorders; Dennis J. Selkoe,Yves Christen Conference proceedings 2003

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,Antibody Therapy Against β-Amyloid to Treat Alzheimer’s Disease,es neuronal protection and improvement in memory tasks. Development of a safe and effective immunization strategy for therapeutic use requires an understanding of the immune system components involved in these responses. A key discovery has been that reduction of AD-like neuropathologies can be obta
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,Antibody Therapy Against β-Amyloid to Treat Alzheimer’s Disease,ined with passive administration of antibodies, and that a T cell response against Aβ is not required. Several mechanisms have been suggested to be involved in efficacy, including antibody Fc-mediated and Fc-independent events; these mechanisms are reviewed here.
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Conference proceedings 2003 treatment. Clinical trials began, but had to be stopped in January 2002 because of serious side effects. The editors‘ objective for this book is not to arouse false hopes for a therapeutic project that must still be proven, but to discuss the available information and the questions it raises..
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