Titlebook: Imaging Mass Spectrometry; Methods and Protocol Laura M Cole,Malcolm R Clench Book 2023Latest edition The Editor(s) (if applicable) and The

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HistoSnap: A Novel Software Tool to Extract ,-Specific Images from Large MSHC Datasets,clever ion-specific image extraction..The package is developed particularly for the untargeted localization/discovery of biomolecules such as endogenous (neuro)secretory peptides on histological sections of biobanked formaldehyde-fixed paraffin-embedded (FFPE) samples straight from tissue banks..Atm

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Update DESI Mass Spectrometry Imaging (MSI),es, without pretreatment. Here we describe the improvements that have been developed to be able to achieve low tens of microns pixel size MSI experiments with high sensitivity for metabolites and lipids from biological tissue sections..In the last decade, DESI mass spectrometry has undergone develop

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Liquid Extraction Surface Analysis Mass Spectrometry Imaging of Denatured Intact Proteins, directly from biological substrates such as tissue sections. LESA MS involves liquid microjunction sampling of a substrate by use of a discrete volume of solvent followed by nano-electrospray ionization. As the technique makes use of electrospray ionization, it lends itself to the analysis of intac

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