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Titlebook: Im Spiegel des Dionysos; Pier Paolo Pasolinis Katrin Holthaus Book 20011st edition Springer-Verlag Berlin Heidelberg 2001 Antike.Euripides.

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involved in drug development.Includes supplementary materia.Chemokine Receptors and NeuroAIDS: Beyond the Co-receptor Function and Links to Other Neuropathologies focuses on unresolved or emerging issues concerning the role of chemokine receptors in neuronal injury and HIV neuropathology, including
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Katrin Holthausof leukocytes to sites of inflammation or injury. In humans, there are approximately 45 chemokines that bind to 19 G-protein-coupled receptors. In addition to mediating cellular migration, chemokines have now been shown to affect many cellular functions including survival, adhesion, invasion, prolif
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Katrin Holthause remains no effective therapy for stroke. A very small group of patients have been treated with some benefit with thrombolytics; however, the short therapeutic time window and the potential for life-threatening side effects limit the effectiveness of this approach. Therefore, with the ultimate aim
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Katrin Holthausof these immunologically relevant proteins. Protein expression in mammalian cells produces high-quality protein compared to other expression methods; however, because structural discovery methods such as cryo-EM-based single particle analysis (SPA) and x-ray crystallography use methods which combine
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Katrin Holthausng evidence for a role of CCR2 and CCR5 receptors in human inflammatory diseases led to a growing interest in CCR2- and CCR5-selective antagonists. In this review, we focus on the recent development of selective CCR2/CCR5 receptor ligands and dual antagonists. Several compounds targeting CCR2, e.g.,
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. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-wor
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