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Titlebook: IgG4-Related Disease; Kazuichi Okazaki Book 2017 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Natu

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Book 2017bundant infiltration of IgG4-positive cells. It consists of nine chapters written by prominent experts in the field and discusses the disease concept, diagnosis and treatment, as well as recent findings on its pathogenesis and pathophysiology. As such, it offers an invaluable source of information for researchers and clinicians alike..
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IgG4-Related Disease978-3-319-52542-6Series ISSN 0070-217X Series E-ISSN 2196-9965
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Marco Lanzillotta,Emanuel Della-Torre,John H. Stone
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The Histopathology of IgG4-Related Disease, confirmation and clinicopathological correlations. A histopathological examination is mandatory to exclude neoplastic or inflammatory conditions that mimic IgG4-related disease. The histological changes that occur are basically similar in any organ manifestation, with several site-specific findings
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The Immunobiology of Immunoglobulin G4 and Complement Activation Pathways in IgG4-Related Disease,exes showed serum elevation of IgG4-type immune complexes in an active disease stage, elevated serum IgG1 concentration, and decreased C3 and C4 values. This inferred that while IgG4 may have had little contribution to complement activation, IgG1 played a prominent role via the classical pathway. On
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Roles of Regulatory T and B Cells in IgG4-Related Disease,G4-RD. We highlight the basic functions of these cells, their changes in patients with various forms of IgG4-RD, and insight gained from animal models of the disease. Based on the evidence accumulated thus far, we proposed a hypothesis for the pathophysiological mechanism of IgG4-RD with respect to
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