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Titlebook: IUPHAR 9th International Congress of Pharmacology: Proceedings, vol 2; William Paton,James Mitchell,Paul Turner Conference proceedings 198

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Glucocorticoid-induced phospholipase inhibitory proteinsids are generally considered as ‘pharmacological actions’ since they are observed when amounts of steroids experimentally used in . or . studies are present in concentrations greater than those found under natural or physiological conditions.
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Receptor mapping by means of interaction energy calculationsic and electronic adaptability of the single members of the series to the receptor. This adaptability can be tested by determination of energies of interaction between drugs and their corresponding receptor binding sites. Hence a correlation between biological activities and binding strengths should be found within an antagonistic drug series.
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Macmillan Publishers Limited 1984
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Phospholipase A2 inhibitors Introduction: an overview acid and a lysophosphoglyceride, is widely distributed in almost all animal tissues. In mammalian cells, the phospholipids are a major source of arachidonic acid for biosynthesis of prostanoids (prostaglandins, thromboxanes, and leukotrienes). Since prostanoids are not stored within cells, biosynth
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