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Titlebook: Hypoxia; Into the Next Millen Robert C. Roach,Peter D. Wagner,Peter H. Hackett Book 1999 The Editor(s) (if applicable) and The Author(s), u

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The Pregnant Altitude Visitor-altitude pregnant visitors. Dehydration, engaging in strenuous exercise before acclimatization, and participation in activities with high risk of trauma are behaviors that may increase the risk of pregnancy complications. Medical and obstetrical conditions which impair oxygen transfer at any step b
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Pulmonary Hemodynamics: Implications for High Altitude Pulmonary Edema (HAPE) Patchy vasoconstriction may expose parts of the capillary bed to high pressure resulting in stress failure of the capillary wall. The development of an inflammatory process may then occur after the initiation of the leak.
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High-Altitude Pulmonary Edema: From Exaggerated Pulmonary Hypertension to a Defect in Transepitheliao had suffered from transient perinatal pulmonary hypertension. We found that these young adults had exaggerated pulmonary vasoconstriction of similar magnitude to that observed in RAPE-susceptible subjects. Surprisingly, however, none of the subjects developed lung edema. These findings strongly su
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Mediators of Cerebral Edemathe release or action of a given autacoid. Among the mediator candidates considered, bradykinin is the only one to meet all criteria. Histamine, arachidonic acid and free radicals including nitric oxide may also be considered mediators of brain edema, but for each of these compounds evidence is less
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Are Arterial, Muscle and Working Limb Lactate Exchange Data Obtained on Men at Altitude Consistent we have shown that liver, heart and muscle mitochondria readily oxidize lactate and contain LDH and MCT1. Accordingly, we have concluded that lactate is the predominant monocarboxylate oxidized by mitochondria .. The model of an “Intra-cellular Lactate Shuttle” is consistent with many of the observat
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