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Titlebook: Hypoxia; Methods and Protocol Daniele M. Gilkes Book 2024 The Editor(s) (if applicable) and The Author(s), under exclusive license to Sprin

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https://doi.org/10.1007/978-3-658-43206-5diagnostic, and therapeutic settings. The scant expression of the antioxidant enzyme NQO1 in normal tissues and its great abundance in malignant counterparts due to the increased redox stress and hypoxia is one such example. Previously, we described a potent nontoxic probe that remains nonfluorescen
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https://doi.org/10.1007/978-3-658-36698-8 phosphorescent oxygen probes is a highly sensitive, noninvasive optical technique for the assessment of molecular oxygen in living cells and tissues. Here, we present a protocol for microscopic mapping of oxygen distribution in a mouse tumor model in vivo. We demonstrate that PLIM microscopy, in co
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