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Titlebook: Hypothalamic Peptide Hormones and Pituitary Regulation; John C. Porter Book 1977 The Editor(s) (if applicable) and The Author(s), under ex

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,What is Intellectual History … ?,bers terminating in the median eminence. There, peptides are discharged into the portal vessels to act as releasing hormones on cells in the adenohypophysis. As yet, however, little evidence is available bearing on axoplasmic transport in those neurons. In this review, principles of axoplasmic trans
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https://doi.org/10.1007/978-94-6300-524-1e been isolated from the hypothalamus which were shown to possess such regulatory functions. For example, the tripeptide thyrotropin releasing hormone (TRH) stimulates the secretion of thyroid stimulating hormone (1,2) and prolactin (3,4), and the decapeptide luteinizing hormone releasing hormone (L
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https://doi.org/10.1057/9780230297531e way for its synthesis by our group (3,5) and by others (6). Intense activity which has been occurring since then in the field of synthesis of analogs of LHRH was caused by the desire to: (a) establish a relationship between the structure and biological activity of this hormone, (b) synthesize anal
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https://doi.org/10.1057/978-1-137-57228-8ne controlling the activity of thyrotropin (TSH) and possibly prolactin-secreting cells, as being (pyro)Glu-His-Pro-NH. (1,2). This achievement was soon followed by the isolation of luteinizing hormone-releasing hormone (LHRH), the neurohormone which stimulates the release of both luteinizing hormon
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What the Philosophy of Biology Is of hormones from the adenohypophysis is well established. Moreover, the activities of these hypothalamic substances have been demonstrated under in vivo as well as in vitro conditions. At least three of these factors, luteinizing hormone releasing hormone (LHRH), thyrotropin releasing hormone (TRH)
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What‘s Wrong with Modern Money Theory?r pituitary gland. The classical studies that led to the formulation of the neurovascular hypothesis (1) and eventually to the isolation, characterization, and synthesis of LHRH (2,3) are widely known. More recent studies showing that antiserum to LHRH, administered systemically, blocks LH secretion
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