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Titlebook: Hypothalamic Peptide Hormones and Pituitary Regulation; John C. Porter Book 1977 The Editor(s) (if applicable) and The Author(s), under ex

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What’s New about the "New" Immigration?have yielded data on the functional changes in the pituitary during the course of the menstrual cycle and have also provided information concerning the contribution of the hypothalamic component of this system.
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Subcellular Compartmentalization of Hypothalamic Peptides: Characteristics and Ontogeny,in the fact that the anatomical location of their target tissues is remote from their site of production and storage. Such polypeptide hormones have been shown to be stored within granules which originate from the Golgi apparatus (6–9).
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Mechanism of Action of Luteinizing Hormone Releasing Hormone and Thyrotropin Releasing Hormone in t-Tyr-Gly-Leu-Arg-Pro-Gly-NH. (3,4). More recently, a tetradecapeptide, H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH, was isolated from ovine and porcine hypothalami (5,6) on the basis of its ability to inhibit growth hormone (GH) release and is called somatostatin or GH release inhibiting hormone.
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https://doi.org/10.1057/9780230297531ogs with prolonged biological activity so that they would be more useful therapeutically than LHRH itself which has a very short halflife of about 2 min, and (c) develop inhibitory antagonistic analogs which would form the basis of new birth control methods.
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https://doi.org/10.1007/978-94-015-1094-3hese organ systems and could, under some circumstances, play pathophysiologic roles as well. In order to study and exploit these biologically important peptides, synthetic analogs have been developed which can be used for several investigational and clinical purposes.
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