Titlebook: Hypercholesterolemia, Hypocholesterolemia, Hypertriglyceridemia, in Vivo Kinetics; Claude L. Malmendier,P. Alaupovic,H. Bryan Brewer Book

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Factors Regulating the Distribution of Cholesterol Between LDL and HDLst be close to equilibrium .. Thus, in terms of regulating the partitioning of cholesteryl esters between LDL and HDL, it is probable that the level of activity of CETP is not normally rate limiting. We have recently reported, however, that the CETP-mediated equilibrium between LDL and HDL can be di

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Human Plasma Lecithin:Cholesterol Acyltransferase (LCAT) On the role of essential carboxyl groups in of a transient tetrahedral adduct which decays with bond cleavage to yield a fatty acylated serine residue. The fatty acid is then internally transacylated to one of two vicinal cysteine residues (Cys-31 and Cys-184) by a mechanism that appears irreversible. Either cysteine residue can then donate

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HDL Receptor-Mediated Cholesterol Efflux from Cells and its Regulattions to the plasma membrane, and the removal of membrane associated cholesterol from cells by exogenous acceptors. It is only the translocation step of this pathway that requires receptor binding of HDL and this is the step that is regulated.

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Distribution of Cholesterol within High Density Lipoproteins Fractionated by Immunoaffinity Chromatoacceptors of cellular cholesterol, the initiating step in reverse cholesterol transport .. In addition, they can act as a repository for lipids shed from triglyceride-rich lipoproteins, greatly facilitating the catabolic removal of these potentially atherogenic lipoprotein particles .. Further subfr

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