Titlebook: Hydrophilic Matrix Tablets for Oral Controlled Release; Peter Timmins,Samuel R. Pygall,Colin D. Melia Book 2014 American Association of Ph

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Applications of Polyethylene Oxide (POLYOX) in Hydrophilic Matrices, is an effective matrix former, with high viscosity and swelling capacity, in addition to its good processing characteristics that aid tablet manufacture. The broad range of molecular weight grades available allows drug release to be tailored for different profiles across a wide range of drug dose a

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A Formulation Development Perspective on Critical Interactions Affecting the Performance of Hydrophrials and other excipients. A precise mechanism by which these interactions occur and how and why they impact on drug release kinetics may be difficult to elucidate and is therefore often poorly understood. Hence, this chapter aims to aid the formulation development process by highlighting and descr

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In Vitro Physical and Imaging Techniques to Evaluate Drug Release Mechanisms from Hydrophilic Matriual dilution of the drug and polymer within the tablet. The rate-controlling processes are physical rather than chemical and are therefore well suited to being followed using physical and imaging methods. This chapter provides an introduction of how modern imaging and more established in vitro techn

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Insulin

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,Evolving Biopharmaceutics Perspectives for Hydrophilic Matrix Tablets: Dosage Form–Food Interactionic matrix oral dosages, and designing robustness into the formulation is key to achieving reproducible behaviour in vivo. This chapter outlines the physiological variables which must be taken into account during the development phase, and describes the different in vitro approaches used in attempts

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on den Protozoen (z.B. bei Gregarinen) bis zu den Säugetieren. Arthropoden und Fische sind die am häufigsten beschriebenen Wirte. Die Microspora (gr. mikros = klein; spora = Same, Keim) gelten als die ursprünglichsten Eukaryoten, da sie keine Organellen endosymbiontischen Ursprungs und keinen typisc

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Peter Timmins Ph.D.,Samuel R. Pygall Ph.D.,Colin D. Melia Ph.D.on den Protozoen (z.B. bei Gregarinen) bis zu den Säugetieren. Arthropoden und Fische sind die am häufigsten beschriebenen Wirte. Die Microspora (gr. mikros = klein; spora = Same, Keim) gelten als die ursprünglichsten Eukaryoten, da sie keine Organellen endosymbiontischen Ursprungs und keinen typisc