| 书目名称 | Humanized Mice for HIV Research | | 编辑 | Larisa Y. Poluektova,J. Victor Garcia,Andrew M. Ta | | 视频video | http://file.papertrans.cn/430/429871/429871.mp4 | | 概述 | Features mouse-to-human xenotransplantation/cross-reactivity of immune systems.Assesses the applicability of different mouse genetic backgrounds for humanization and human immune system function.Writt | | 图书封面 |  | | 描述 | .Over the last several years the field of humanized mice has matured and developed into an essential component of translational research for HIV/AIDS. Humanized mice serve both as vehicles for discovery and as highly sophisticated platforms for biomedical research. In addition, humanized mice have demonstrated outstanding potential for the investigation of critical aspects of the infection and pathogenesis of the hepatitis and herpes viruses, as well as highly relevant microbial infections such as tuberculosis and malaria. .Humanized Mice for HIV Research. provides a comprehensive presentation of the history, evolution, applications, and current state of the art of this unique animal model. An expansion of twelve review articles that were published in .Humanized Mice. by Springer in 2008 (Eds: Nomura T, Watanabe T, Habu S), this book expertly captures the outstanding progress that has been made in the development, improvement, implementation, and validation of humanized mouse models. The first two parts of this book cover the basics of human-to-mouse xenotransplantation biology, and provide critical information about human immune cell development and function based on individual mo | | 出版日期 | Book 2014 | | 关键词 | HIV; Immune system function; Mouse-to-human xenotransplantation; humanized mice | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4939-1655-9 | | isbn_softcover | 978-1-4939-4563-4 | | isbn_ebook | 978-1-4939-1655-9 | | copyright | Springer Science+Business Media New York 2014 |
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