| 书目名称 | Human T Cell Clones | | 副标题 | A New Approach to Im | | 编辑 | Marc Feldmann,Jonathan R. Lamb,James N. Woody | | 视频video | | | 丛书名称 | Experimental Biology and Medicine | | 图书封面 |  | | 描述 | Most complex biological systems, such as enzyme pathways, are effec tively controlled near the beginning of the process. There is increasing evidence that the same is true for the immune system, with the initial interactions between antigen, antigen-presenting cells, and T cells hav ing a paramount influence on the ensuing events. Thus, analysis of the early stages of the immune responses has been a preoccupation of many immunologists. This has been considerably aided by the capac ity to expand these early events, and ‘immortalize‘ them as clones of T cells, for detailed analysis. The discovery by Morgan, Ruscetti, and Gallo (Science 193, 1007, 1976) of T-cell growth factor (now termed interleukin-2 or IL-2) has had a major impact in immunology that is far from over. The greater ease of handling murine tissues experimentally, with the availability of more precisely defined reagents such as inbred strains, has meant that, to date, most of the work on long-term T-cell cultures has been per formed in the mouse, as summarized by Fathman and Fitch (eds. , Iso lation, Characterization and Utilization of T Lymphocyte Clones, Aca demic Press, NY, 1982). However, the limitations of wo | | 出版日期 | Book 1985 | | 关键词 | AIDS; Antigen; autoimmune disease; interferon; transplantation | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4612-4998-6 | | isbn_softcover | 978-1-4612-9391-0 | | isbn_ebook | 978-1-4612-4998-6 | | copyright | The Humana Press Inc. 1985 |
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发表于 2025-3-21 18:24:38
