Titlebook: Human Retrotransposons in Health and Disease; Gael Cristofari Book 2017 Springer International Publishing AG 2017 Epigenetics.Genome.Germl

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Roles of Endogenous Retrovirus-Encoded Syncytins in Human Placentation,ay important roles in the development of a healthy and functional placenta. Indeed, the conserved fusogenic properties that characterize Syncytin proteins among the mammalian clade are believed to be crucial for the formation of the syncytiotrophoblast (STB) layer of the placenta. Moreover, human Sy

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Alu-Alu Recombinations in Genetic Diseases,s in the genome. In addition to their ability to cause genetic diseases through insertional mutagenesis, Alu elements contribute to genetic instability due to their sequence similarity and high density in the genome. Nonallelic homologous recombination between Alu elements occurs in somatic and germ

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Retrotransposon-Driven Transcription and Cancer,at the forefront of research into the role of these elements in cancer. Indeed, it is intuitive to envisage the mutational and cancer-promoting effects of retrotransposition, given the dramatic effects on genome structure inherent in mobilization. Nevertheless, recent work has revealed that retrotra

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Contribution of Retrotransposable Elements to Aging, cells. RTEs have contributed to the evolution of their hosts by creating germline genomic diversity, but under most circumstances retrotransposition has deleterious consequences. Our understanding of RTE activity in somatic cells and tissues has lagged, largely because we lacked effective tools to

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Ian R. Adams auf Beobachtungen während einer mehrmonatlichen Studienreise in den Vereinigten Staaten, die im Auftrage des Vereins für die bergbaulichen Interessen im Oberbergamtsbezirk Dortmund im Laufe dieses Sommers von Herrn Bergassessor Schulz-Briesen und dein Verfasser ausgeführt wurde. Um die für die Verw

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