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Titlebook: Human Identification: The Use of DNA Markers; Bruce S. Weir Book 1995 Springer Science+Business Media Dordrecht 1995 Allele.DNA.PCR.evolut

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书目名称Human Identification: The Use of DNA Markers
编辑Bruce S. Weir
视频video
丛书名称Contemporary Issues in Genetics and Evolution
图书封面Titlebook: Human Identification: The Use of DNA Markers;  Bruce S. Weir Book 1995 Springer Science+Business Media Dordrecht 1995 Allele.DNA.PCR.evolut
描述The ongoing debate on the use of DNA profiles to identifyperpetrators in criminal investigations or fathers in paternitydisputes has too often been conducted with no regard to soundstatistical, genetic or legal reasoning. The contributors to .HumanIdentification: The Use of. .DNA Markers. all have considerableexperience in forensic science, statistical genetics or jurimetrics,and many of them have had to explain the scientific issues involved inusing DNA profiles to judges and juries. Although the authors holddiffering views on some of the issues, they have all produced accountswhich pay due attention to the, sometimes troubling, issues ofindependence of components of the profiles and of populationsubstructures. The book presents the considerable evolution of ideasthat has occurred since the 1992 Report of the National ResearchCouncil of the U.S. ..Audience:. Indispensable to forensic scientists, laying out theconcepts to all those with an interest in the use of geneticinformation. The chapters and exhaustive bibliography are vitalinformation for all lawyers who must prosecute or defend DNA cases,and to judges trying such cases. .
出版日期Book 1995
关键词Allele; DNA; PCR; evolution; genetic information; genetics
版次1
doihttps://doi.org/10.1007/978-0-306-46851-3
isbn_softcover978-94-017-1803-5
isbn_ebook978-0-306-46851-3Series ISSN 0929-712X
issn_series 0929-712X
copyrightSpringer Science+Business Media Dordrecht 1995
The information of publication is updating

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The effect of relatedness on likelihood ratios and the use of conservative estimates, a match in DNA profiles is given by the likelihood ratio. This, in turn, depends upon the probability that a match would be produced if the suspect is innocent. This probability could be strongly affected by the possibility of relatedness between the suspect and the true source of the scene-of-crim
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Inference of population subdivision from the VNTR distributions of New Zealanders,vision. The initial null hypothesis, that the population sample is homogeneous across ethnic groups, is easily rejected by likelihood ratio tests. Beyond this, methods for quantifying subdivision can be based on the probability of drawing alleles identical by descent (..),probabilities of matching m
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Assessing probability of paternity and the product rule in DNA systems,bability of paternity, .). Notwithstanding some initial fanfare, statistical inference is a necessary component of DNA-based paternity tests because band patterns may be rare but not yet unique, and even rare events in a vacuum are meaningless. The genetic match must be combined with other evidence
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