Titlebook: Host-Fungal Interactions; Methods and Protocol Elaine Bignell Book 2021 Springer Science+Business Media, LLC, part of Springer Nature 2021

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Quantifying Receptor-Mediated Phagocytosis and Inflammatory Responses to Fungi in Immune Cells,macrophages, control and regulate immunity to fungi. These cellular responses are initiated when conserved pathogen components, known as pathogen-associated molecular patterns (PAMPs), are recognized by pattern-recognition receptors (PRRs), which include members of the C-type lectin receptor (CLR) f

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Measuring In Vivo Neutrophil Trafficking Responses During Fungal Infection Using Mixed Bone Marrow he molecular factors that mediate neutrophil chemotaxis is therefore critical for our understanding of disease pathogenesis and the mechanisms underlying protective immunity. Here, we describe a protocol that enables analysis of neutrophil recruitment from the blood into fungal-infected organs in vi

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Murine Models of Hematopoietic Cell Transplantation to Investigate Fungal Infections,cell transplantation (HCT) is described. This model can be used to investigate the establishment and progression of fungal infections after HCT and to elucidate how different transplant variables affect the recovery of host immunity.