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Titlebook: Host Defenses and Immunomodulation to Intracellular Pathogens; Toby K. Eisenstein (Professor of Microbiology and Book 1988 Springer Scien

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Use of Recombinant Vaccinia Viruses to Examine Cytotoxic T Lymphocyte Recognition of Individual Vira with class I major histocompatibility complex (MHC) molecules, and act by either directly lysing cells bearing the foreign antigen, or by releasing molecules with anti-viral and/or anti-tumor activities.. Understanding of CTL has been hindered by difficulties in identifying which foreign antigens a
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Role of Natural Killer Cells in the Early Clearance of , in Miceection, bear the Thy-1 antigen (1) and are H-2 restricted. Further, H-2 restricted cytotoxic T-cells functional . also arise at approximately the same time (2), and are believed to belong to the same lineage as those which transfer immunity (3). Examination of the kinetics of the immune response, ho
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Loss of Tumorigenicity Following , MuLV Infection is Associated with Induction of Peritoneal Naturaled rejection of transplantable thymomas (RL-cell line) and subsequent tumor immunity in syngeneic mouse recipients. FLV-infected RL-cells (RL-FLV) were unaltered in their . growth, and grew progressively to kill sublethally irradiated animals and nude mice. Primary RL-FLV rejection was due to induct
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Validation of a Role for Endogenously Produced IFNγ in Resolution of , Infection in Miceastic cells (1–6). Three to five years ago, work from several laboratories indicated that IFNγ was one of the major classes of lymphokines capable of activating macrophages under well-defined . conditions (7–14). Recently, there has been an explosive growth of experiments directed at defining IFNγ’s
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