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Titlebook: Host Defense Peptides and Their Potential as Therapeutic Agents; Richard M. Epand Book 2016 Springer International Publishing Switzerland

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发表于 2025-3-21 16:26:03 | 显示全部楼层 |阅读模式
书目名称Host Defense Peptides and Their Potential as Therapeutic Agents
编辑Richard M. Epand
视频video
概述Summarizes the latest developments in host defense peptides research.Explores potential therapeutic applications of host defense peptides.Written by international experts of host defense peptide resea
图书封面Titlebook: Host Defense Peptides and Their Potential as Therapeutic Agents;  Richard M. Epand Book 2016 Springer International Publishing Switzerland
描述.This book offers an overview of our current understanding of host defense peptides and their potential for clinical applications as well as some of the obstacles to this. The chapters, written by leading experts in the field, detail the number and diversity of host defense peptides, and discuss the therapeutic potential not only of antibacterial, but also of antifungal, antiviral, plant antimicrobial and anticancer host defense peptides. The authors provide new insights into their mechanisms of action and their immunomodulatory properties, and review recent advances in the design of novel therapeutic molecules. Lastly, their potential to prevent preterm births and .Staphylococcus aureus .infections is highlighted... The book is of interest to researchers, industry and clinicians alike..
出版日期Book 2016
关键词Drug discovery; Innate immunity; Peptide engineering; Therapeutic applications; Antibiotics; Immunomodula
版次1
doihttps://doi.org/10.1007/978-3-319-32949-9
isbn_softcover978-3-319-81406-3
isbn_ebook978-3-319-32949-9
copyrightSpringer International Publishing Switzerland 2016
The information of publication is updating

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Antiviral Host Defence Peptidesiral molecules. The antiviral activity of cationic host defence peptides is of significant interest as novel therapeutics for treating viral infection and predominantly due to their broad spectrum antiviral activity. These peptides also display powerful immunomodulatory activity and are key mediator
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Anticancer Peptides: Prospective Innovation in Cancer Therapying over time due to the development of severe side-effects that simultaneously condition adherence to therapy. Biologically active peptides, in particular antimicrobial peptides (AMPs), are versatile molecules in terms of biological activities. The cytotoxic activities of several AMPs turn this gro
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Plant Antimicrobial Peptidesesticides. Despite plant’s multilayer of innate defence against pathogens, often the latter are able to penetrate and establish themselves on plant host. The discovery of antimicrobial peptides (AMPs) has the promise of durable defence by quickly eliminating pathogens through membrane lysis. AMPs ch
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Host Defense Peptides and the Eicosanoid Cascadeionic and amphipathic short polypeptides with typical length between 15 and 40 amino acid residues. HDPs not only possess potent antimicrobial activity against a variety of pathogens, they are also widely recognized for their multifunctional roles in both the innate and adaptive immune responses. On
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Bacterial Resistance to Host Defence Peptidesctions and minor injuries to kill is a very real possibility. A potential solution to this problem is the development of host defence peptides, which are endogenous antibiotics that kill microbes via membranolytic action, based in part on the belief that microbes were unlikely to develop resistance
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Engineered OAKs Against Antibiotic Resistance and for Bacterial Detections becomes evermore urgent. Membrane-active compounds (MACs) are currently gaining interest for their potential to address various antibiotic resistance challenges. Since MACs are able to target multiple vital bacterial functions simultaneously, they may have the advantage of fighting the infection w
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How to Teach Old Antibiotics New Tricks target generic features common to the membranes of many pathogens. As a result, development of resistance to such natural defenses is inhibited compared to conventional antibiotics. The disadvantage of AMPs, however, is that they are often not very potent. In contrast, traditional antibiotics typic
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