Titlebook: Hormonally Active Brain Peptides; Structure and Functi Kenneth W. McKerns,Vladimir Pantić Book 1982 Springer Science+Business Media New Yor

instructive

Steroids and Membrane-Associated Events in Neurons and Pituitary Cells,ge, 1971; Mowles ., 1971; Wade and Feder, 1972; for review see Warembourg, 1978). Sex steroids have been shown to control or modulate a number of functions in the central nervous system (CNS). A fundamental argument against a single mechanism of action for sex steroids is the various delays observed

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In Vitro Synthesis of Hypothalamic Neurophysin Precursors,s), are treated with “catalytic” (substoichio-metric) amounts of disulfide-reducing agent, they are inactivated readily, due to scrambling of the disulfides to nonnative combinations (Chaiken ., 1975). Further, this process is speeded up by the inclusion of microsomal disulfide interchange enzyme.

Aprope

Gonadotropin-Releasing Hormone Release into Hypophyseal Portal Blood and Mechanism of Action,t effects on the ovary and testis, and these effects may be related to the presence in the organs of a substance that is biologically, but not immunologically, similar to GnRH (Ying and Guillemin, 1980; Sharpe and Fraser, 1980; Sharpe ., 1981).

敲竹杠

Structure and Function Relationships among Synthetic Enkephalin Analogues,y ., 1975; Li and Chung, 1976), was shown to possess morphinelike activity (Bradbury ., 1976a; Cox ., 1976) and was named .-endorphin (Li and Chung, 1976). The isolation and opioid activity of .-LPH-(61 – 76) (Guillemin ., 1976) and .-LPH-(61 – 77) (Lazarus ., 1976), called . and .-endorphin, respectively, were also described.

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Hormonal Regulation of and Ionic Requirements for in Vitro Release of Hypothalamic Peptides,tions (Hökfelt ., 1980; Elde and Hökfelt, 1978; Fuxe, 1965) of several neuropeptides and neurotransmitters within these hypothalamic areas made it tempting to investigate neurotransmitter-neuropeptide interactions and their possible involvement in the adenohypophy-seal regulation (Kordon ., 1980; Weiner and Ganong, 1978; Schally, 1978).

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Stress, Corticoliberin (CRF), and Glucocorticoids in the Regulation of ACTH Release, addition, feedback loops, both hormonal and neural, convey information about the performance of the various components of the hypothalamo-pituitary-adrenocortical system. Recently, a great deal of . information became available about the various components and the mechanisms involved in the organization of their interrelationships.

Paraplegia

Steroid Antagonism of Melanosome Movements Induced by Neuropeptides,ological changes in man (Woodbury, 1958). Furthermore, glucocorticoids modify the excitability of nerve cells in several brain regions (Chambers ., 1963; Pfaff ., 1971; Phillips and Dafny, 1971; Conforti and Feldman, 1975).

obtuse

Is VIP a Neuroregulator or a Hormone?,, glycogenosis and lipolysis, relaxation of smooth muscle and stimulation of neuronal activity. It acts at different levels: on the gastrointestinal, the respiratory, the cardiovascular, the urogenital, the central and peripheral nervous system, on endocrine functions and metabolism (see review by Rosselin ., 1980).