Titlebook: Hormonal Carcinogenesis; Proceedings of the F Jonathan J. Li,Satyabrata Nandi,Sara Antonia Li Conference proceedings 1992 Springer-Verlag N

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Diethylstilbestrol (DES) Syndrome: Present Status of Animal and Human Studieso diethylstilbestrol (DES) ingested by their mothers during the first trimester of pregnancy. Although this relationship is generally accepted for patients in the U.S. as well as in several other countries (1), the epidemiological basis is still occasionally questioned and defended (2,3). Other fact

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The Conjoint Actions of Androgens and Estrogens in the Induction of Proliferative Lesions in the Ratchanges in the sex hormone milieu may be the common cause of prostatic cancer development in man Several lines of evidence furnish support for this credence. First, circulating levels of free testosterone (T) in men decline with age while those of free 17ß-estradiol (E.) remain unchanged, thus resul

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A Novel Protein Kinase Activity Identified from Human Breast Cancer Cell Linesion (1,2). They catalyze the covalent transfer of phosphate from two common donors, ATP or GTP, to serine, threonine, and tyrosine residues located on its own molecule, endogenous cellular or exogenous protein acceptors, or synthetic aminoacidic sequences. Regarding their function it is well establi

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Estrous Cycle Modification of Rat Mammary Carcinoma Inductionr, excess estrogen has been proposed to lead to increased proliferation of mammary epithelium (2). We have asked the question of whether a hormonally induced alteration(s) in cell proliferation is an integral feature of the multiple rate-limiting events (3) that underlie the chemically induced trans